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Oskar-A — EPR effect

#epr #tumor
Published: 2018-06-20 18:03:15 +0000 UTC; Views: 451; Favourites: 5; Downloads: 0
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Description An illustration I did for work ( spagonanomedical.se/en/). It illustrates how the blood vessels (capillaries) in a tumor are of poor quality so nanoparticles (blue and about 1000 times to big for the scale) can leak out into the tissue. This is called the EPR effect (Enhanced permeation and Retention). The leakiness combined with poor lymph drainage allows us to deliver nanoparticles with a contrast enhancing content to the tumors so we can make nice images of nasty tumors. ...and everything was modeled in Blender and rendered with Cycles.
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Comments: 11

LuxXeon [2018-07-23 16:29:52 +0000 UTC]

This kind of thing is probably the most difficult of all genres of 3d art.  Science and medical modeling need to be spot on accurate, and artistic liberty is at a bare minimum usually.  I think this looks amazing, but I wouldn't know what it's really supposed to look like anyway.  haha.

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Oskar-A In reply to LuxXeon [2018-07-23 18:18:09 +0000 UTC]

Thanks. This kind of image is more explanatory than accurate so quite a lot of liberty is exercised. The tumor looks quite natural but the vessel is way too big and the nanoparticles which would be colorless are way, way too big.

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LuxXeon In reply to Oskar-A [2018-07-23 21:50:19 +0000 UTC]

Thanks for clarifying.  Still, it's extremely impressive.  I know someone who creates models for a medical manufacturing company.  He works in-house as their CAD and 3d ad designer.  He makes a lot of money, but the work is extremely laborious and must be perfectly precise to the real world counterparts.  Very painstaking work I would imagine.  He's well compensated, but always under some very extreme deadlines and complex projects.  He does all their 3d modeling, which also requires photoscanning as well as precise CAD and polygonal models, and also uses the models in various video animations and motion graphics for the company too.  Once a job is done, the company allows him to put the models up on various warehouse sites to sell to other companies or artists, and he gets a piece of that profit as well.

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Oskar-A In reply to LuxXeon [2018-07-24 17:52:13 +0000 UTC]

Unfortunately I am more of a concept person so I'd probably lose patience before completing. I am well compensated for my concepts though, even if they are more scientific than artistic most of the time.

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LuxXeon In reply to Oskar-A [2018-07-24 20:14:38 +0000 UTC]

That's excellent.  Keep up the great works.  

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Ariel-X [2018-06-27 09:03:19 +0000 UTC]

I really like the organic material, it truly looks fantastic and eeew, eew, eeew

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DixieRamone [2018-06-22 08:21:19 +0000 UTC]

Excellent work & detailed explanation. Thank you for sharing!


Does it matter where in the body the tumor is located? Is it imaged in a CT scan, or some other test?

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Oskar-A In reply to DixieRamone [2018-06-22 08:27:48 +0000 UTC]

Thanks. Most malignant tumors have this property. The scan is MRI. Magnetic imaging of the water in the body. It will matter greatly where in the body the tumor sits,

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Linwelly [2018-06-21 11:57:47 +0000 UTC]

Wow, cool, very well done, you are really expert with that organic stuff

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Oskar-A In reply to Linwelly [2018-06-21 15:13:09 +0000 UTC]

Thanks. Well, I am an organic chemist so that may explain things .

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Linwelly In reply to Oskar-A [2018-06-25 20:19:19 +0000 UTC]

Indeed, but knowing is not the skill to make it look right, it just really helps

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